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Download Bioreactor Engineering Research and Industrial Applications by Qin Ye, Jie Bao, Jian-Jiang Zhong PDF

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By Qin Ye, Jie Bao, Jian-Jiang Zhong

This e-book assessment sequence provides present developments in smooth biotechnology. the purpose is to hide all facets of this interdisciplinary know-how the place wisdom, tools and services are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and machine technology. Volumes are geared up topically and supply a complete dialogue of advancements within the respective box over the last 3-5 years. The sequence additionally discusses new discoveries and purposes. designated volumes are devoted to chosen subject matters which specialise in new biotechnological items and new methods for his or her synthesis and purification. typically, distinct volumes are edited by way of recognized visitor editors. The sequence editor and writer will notwithstanding constantly be happy to obtain feedback and supplementary details. Manuscripts are authorised in English.

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Additional info for Bioreactor Engineering Research and Industrial Applications I: Cell Factories

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Although the respiration is universal among all aerobic organisms, inefficient electron transfer via the respiratory complexes results in one electron reduction of diatomic oxygen, a phenomenon known to generate toxic ROS [191]. Since NADPH plays an important role for detoxification of ROS, some prokaryotic microorganisms such as E. coli produce NADPH at ICDH in the TCA cycle together with the reactions at G6PDH, 6PGDH, and possibly at Mez. The αKG is a key participant in the detoxification of ROS with concomitant formation of succinate, where succinate is a biomarker for oxidative stress [191].

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Toya Y, Ishii N, Nakahigashi K, Tomita M, Shimizu K (2010) 13C-metabolic flux analysis for batch culture of Escherichia coli and its Pyk and Pgi gene knockout mutants based on mass isotopomer distribution of intracellular metabolites. Biotechnol Prog 26:975–992 95. Schuetz R, Zamboni N, Zampieri M, Heinemann M et al (2012) Multidimensional optimality of microbial metabolism. Science 336:601–604 96. Enjalbert B, Letisse F, Portais J-C (2013) Physiological and molecular timing of the glucose to acetate transition in Escherichia coli.

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